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Can you use vitamin C and benzoyl peroxide together?

Best used at different times

Use them at different times of day. Benzoyl peroxide is an oxidising agent, and vitamin C is an antioxidant that oxidises easily, so applying them together may waste the vitamin C.

Why

Vitamin C works by being oxidised in place of your skin. Put it on at the same time as benzoyl peroxide and the two can react on the skin, leaving less vitamin C to do its job. Both can also be irritating.

How to use them

  • Vitamin C in the morning under sunscreen, benzoyl peroxide in the evening.
  • Or use a benzoyl peroxide wash and rinse it off before applying vitamin C.

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Other combinations

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Last reviewed 20 Oct 2026.

This is educational information, not medical advice. Introduce one new active at a time and patch test. If you use prescription skincare, or are pregnant or breastfeeding, check with your GP, pharmacist or dermatologist first.