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Can you use vitamin C with vitamin E and ferulic acid?

Yes — they work well together

Yes. This is one of the best-studied skincare combinations: vitamin E and ferulic acid help stabilise vitamin C and boost its antioxidant protection.

Why

In laboratory tests, adding 0.5% ferulic acid to a 15% vitamin C and 1% vitamin E solution made the vitamins more stable and roughly doubled the protection it gave skin against UV damage (Lin 2005). A later small study on human skin found the same combination reduced sunburn reactions and UV-related DNA damage (Murray 2008).

It doesn't replace sunscreen. It works differently and adds to the protection sunscreen gives.

How to use them

  • Use a serum that already contains all three in the morning, then moisturiser and SPF.
  • Store it closed and away from light. If it turns dark orange or brown, the vitamin C has oxidised.

Read more about each ingredient

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Other combinations

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Sources

  1. Lin FH et al. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. J Invest Dermatol, 2005.
  2. Murray JC et al. A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation. J Am Acad Dermatol, 2008.

Last reviewed 20 Oct 2026.

This is educational information, not medical advice. Introduce one new active at a time and patch test. If you use prescription skincare, or are pregnant or breastfeeding, check with your GP, pharmacist or dermatologist first.